DoseCompass / Medications / Xelstrym
Xelstrym
dextroamphetamine transdermal patch · Amphetamine class
The only amphetamine patch: worn for up to 9 hours, delivering dextroamphetamine through the skin. Useful when swallowing pills is a problem or GI absorption is unreliable.
*Approximate U.S. cash price for a 30-day supply with a free discount card, mid-2026. Compare current prices on GoodRx.
Available strengths
4.5 mg · 9 mg · 13.5 mg · 18 mg — nominal dose delivered over a 9-hour wear
How long it lasts
Typical effective duration is 9–11 hours (worn up to 9 hours; effects persist ~2 hours after removal), though metabolism, sleep, and food timing move this meaningfully for individuals. See how it compares to every other product on the duration chart.
Approximate dose equivalents
Every marketed Xelstrym strength translated into five common alternatives (total-daily-dose basis). Cross-class figures (†) use the rough ~2:1 amphetamine↔methylphenidate heuristic and are the least precise.
| Xelstrym | Adderall IR | Adderall XR | Vyvanse | Ritalin IR | Concerta | Focalin |
|---|---|---|---|---|---|---|
| 4.5 mg | ≈ 6 | ≈ 6 | ≈ 15 | ≈ 9 † | ≈ 10.8 † | ≈ 4.5 † |
| 9 mg | ≈ 12 | ≈ 12 | ≈ 30 | ≈ 18 † | ≈ 21.7 † | ≈ 9 † |
| 13.5 mg | ≈ 18 | ≈ 18 | ≈ 45 | ≈ 27 † | ≈ 32.5 † | ≈ 13.5 † |
| 18 mg | ≈ 24 | ≈ 24 | ≈ 60 | ≈ 36 † | ≈ 43.4 † | ≈ 18 † |
All values ≈ mg/day, from published cross-titration references and product labeling. For a custom dose or frequency, use the interactive converter.
Common questions
What strengths does Xelstrym come in?
Xelstrym (dextroamphetamine transdermal patch) is available in: 4.5, 9, 13.5, 18 mg. Patch strengths are the nominal dose delivered over a 9-hour wear time.
How long does Xelstrym last?
Typical effective duration is 9–11 hours, though individual metabolism varies. Effects continue roughly 2 hours after the patch is removed.
Is there a generic Xelstrym?
No — it is currently brand-only, typically $380–460/month cash. The manufacturer copay card can substantially reduce the price for commercially insured patients.
What is Xelstrym equivalent to?
As a total-daily-dose approximation, Xelstrym 13.5 mg is ≈ 18 mg Adderall XR, ≈ 45 mg Vyvanse, ≈ 27 mg/day methylphenidate (Ritalin). These are discussion figures from published cross-titration references — cross-class conversions are rougher, and actual switches are titrated by your prescriber.