DoseCompass / Medications / Dexedrine Spansule
Dexedrine Spansule
dextroamphetamine ER · Amphetamine class
The extended-release capsule form of dextroamphetamine, covering 6–8 hours. An older product that fewer pharmacies stock, but a useful same-molecule alternative during Vyvanse shortages.
*Approximate U.S. cash price for a 30-day supply with a free discount card, mid-2026. Compare current prices on GoodRx.
Available strengths
5 mg · 10 mg · 15 mg
How long it lasts
Typical effective duration is 6–8 hours, though metabolism, sleep, and food timing move this meaningfully for individuals. See how it compares to every other product on the duration chart.
Approximate dose equivalents
Every marketed Dexedrine Spansule strength translated into five common alternatives (total-daily-dose basis). Cross-class figures (†) use the rough ~2:1 amphetamine↔methylphenidate heuristic and are the least precise.
| Dexedrine Spansule | Adderall IR | Adderall XR | Vyvanse | Ritalin IR | Concerta | Focalin |
|---|---|---|---|---|---|---|
| 5 mg | ≈ 6.7 | ≈ 6.7 | ≈ 16.7 | ≈ 10 † | ≈ 12 † | ≈ 5 † |
| 10 mg | ≈ 13.3 | ≈ 13.3 | ≈ 33.3 | ≈ 20 † | ≈ 24.1 † | ≈ 10 † |
| 15 mg | ≈ 20 | ≈ 20 | ≈ 50 | ≈ 30 † | ≈ 36.1 † | ≈ 15 † |
All values ≈ mg/day, from published cross-titration references and product labeling. For a custom dose or frequency, use the interactive converter.
Common questions
What strengths does Dexedrine Spansule come in?
Dexedrine Spansule (dextroamphetamine ER) is available in: 5, 10, 15 mg.
How long does Dexedrine Spansule last?
Typical effective duration is 6–8 hours, though individual metabolism varies.
Is there a generic Dexedrine Spansule?
Yes. With a free discount card, a typical 30-day supply runs about $40–90 without insurance.
What is Dexedrine Spansule equivalent to?
As a total-daily-dose approximation, Dexedrine Spansule 10 mg is ≈ 13.3 mg Adderall XR, ≈ 33.3 mg Vyvanse, ≈ 20 mg/day methylphenidate (Ritalin). These are discussion figures from published cross-titration references — cross-class conversions are rougher, and actual switches are titrated by your prescriber.